4JJN

Crystal structure of heterochromatin protein Sir3 in complex with a silenced yeast nucleosome

Exp. Method X-ray
Resolution, Å 3.09
Release Date 2013-05-15
Update Date 2024-02-28
Authors Wang, F., Li, G., Altaf, M., Lu, C., Currie, M.A., Johnson, A., Moazed, D.
Publication PMID: 23650358
doi 10.1073/pnas.1300126110
RCSB PDB 4JJN
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal E canonical H3 Saccharomyces cerevisiae P61830
Distal A canonical H3 Saccharomyces cerevisiae P61830
H4 Proximal F canonical H4 Saccharomyces cerevisiae P02309
Distal B canonical H4 Saccharomyces cerevisiae P02309
H2A Proximal G H2A.X Saccharomyces cerevisiae P04912
Distal C H2A.X Saccharomyces cerevisiae P04912
H2B Proximal H canonical H2B Saccharomyces cerevisiae P02294
Distal D canonical H2B Saccharomyces cerevisiae P02294
Other proteins:
Chain Name UID
K Regulatory protein SIR3 P06701
L Regulatory protein SIR3 P06701
DNA:
Chain Variant Length
I 601 146
J 601 146

H3

H4

H2A

H2B

DNA

Other


Chain Bfactor

Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.