3TU4

Crystal structure of the Sir3 BAH domain in complex with a nucleosome core particle.

Exp. Method X-ray
Resolution, Å 3
Release Date 2011-11-23
Update Date 2024-02-28
Authors Armache, K.J., Garlick, J.D., Canzio, D., Narlikar, G.J., Kingston, R.E.
Publication PMID: 22096199
doi 10.1126/science.1210915
RCSB PDB 3TU4
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal E canonical H3 Xenopus laevis P84233
Distal A canonical H3 Xenopus laevis P84233
H4 Proximal F canonical H4 Xenopus laevis P62799
Distal B canonical H4 Xenopus laevis P62799
H2A Proximal G canonical H2A Xenopus laevis P06897
Distal C canonical H2A Xenopus laevis P06897
H2B Proximal H canonical H2B Xenopus laevis P02281
Distal D canonical H2B Xenopus laevis P02281
Other proteins:
Chain Name UID
K Regulatory protein SIR3 P06701
L Regulatory protein SIR3 P06701
DNA:
Chain Variant Length
I 601 146
J 601 146

H3

H4

H2A

H2B

DNA

Other


Chain Bfactor

Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.