1ZLA

X-ray Structure of a Kaposi's sarcoma herpesvirus LANA peptide bound to the nucleosomal core

Exp. Method X-ray
Resolution, Å 2.9
Release Date 2006-02-28
Update Date 2023-08-23
Authors Barbera, A.J., Chodaparambil, J.V., Kelley-Clarke, B., Joukov, V., Walter, J.C., Luger, K., Kaye, K.M.
Publication PMID: 16469929
doi 10.1126/science.1120541
Related structures 1aoi, 1f66, 1kx3, 1kx4, 1kx5
RCSB PDB 1ZLA
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal A canonical H3 Xenopus laevis P84233
Distal E canonical H3 Xenopus laevis P84233
H4 Proximal B canonical H4 Xenopus laevis P62799
Distal F canonical H4 Xenopus laevis P62799
H2A Proximal C canonical H2A Xenopus laevis P06897
Distal G canonical H2A Xenopus laevis P06897
H2B Proximal D canonical H2B Xenopus laevis P02281
Distal H canonical H2B Xenopus laevis P02281
Other proteins:
Chain Name UID
K latent nuclear antigen Q9DUM3
DNA:
Chain Variant Length
I alphasat_146 146
J alphasat_146 146

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.