0 |
8OW1 |
EM |
3.70 |
2023-08-09 |
hexamer |
1 |
cenH3 |
canonical_H4 |
H2A.X |
canonical_H2B |
|
601_modified |
153 |
Cryo-EM structure of the yeast Inner kinetochore bound to a CENP-A nucleosome. |
Dendooven, T., Zhang, Z., Yang, J., McLaughlin, S.H., Schwab, J., Scheres, S.H.W., Yatskevich, S., Barford, D. |
10.1126/sciadv.adg7480 |
37506202 |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Xenopus laevis |
2023 |
Centromere-binding protein 1, Centromere DNA-binding protein complex CBF3 subunit B, Inner kinetochore subunit MCM16, Inner kinetochore subunit CTF3, Inner kinetochore subunit MCM22, Inner kinetochore subunit IML3, Inner kinetochore subunit CHL4, Inner kinetochore subunit MCM21, Inner kinetochore subunit CTF19, Inner kinetochore subunit OKP1, Suppressor of kinetochore protein 1, Inner kinetochore subunit CNN1, Inner kinetochore subunit AME1, Inner kinetochore subunit WIP1, Inner kinetochore subunit NKP1, Inner kinetochore subunit NKP2, Histone H2A.1 |
CBF3, Cell cycle, Transcription-associated, Centromere-associated, Nuclear division, CCAN, Kinetochore |
P17106, P40969, Q12262, Q12748, P47167, P38265, P38907, Q06675, Q02732, P53298, P52286, P43618, P38313, Q2V2P8, Q12493, Q06162, P04911 |
P02293, P02309, P04911, P36012 |
0.165 |
1 |
6QLD |
EM |
4.15 |
2019-10-02 |
octamer |
1 |
cenH3 |
canonical_H4 |
H2A.X |
canonical_H2B |
|
601 |
124 |
Structure of inner kinetochore CCAN-Cenp-A complex |
Yan, K., Yang, J., Zhang, Z., McLaughlin, S.H., Chang, L., Fasci, D., Ehrenhofer-Murray, A.E., Heck, A.J.R., Barford, D. |
10.1038/s41586-019-1609-1 |
31578520 |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Xenopus laevis |
2019 |
Inner kinetochore subunit MIF2, Inner kinetochore subunit MCM16, Inner kinetochore subunit CTF3, Inner kinetochore subunit MCM22, Inner kinetochore subunit IML3, Inner kinetochore subunit CHL4, Inner kinetochore subunit MCM21, Inner kinetochore subunit CTF19, Inner kinetochore subunit OKP1, Inner kinetochore subunit AME1, Inner kinetochore subunit NKP1, Inner kinetochore subunit NKP2 |
Cell cycle, Centromere-associated, Kinetochore, Nuclear division, CCAN |
P35201, Q12262, Q12748, P47167, P38265, P38907, Q06675, Q02732, P53298, P38313, Q12493, Q06162 |
P02293, P02309, P04911, P02294, P36012 |
0.328 |
2 |
7K7G |
EM |
4.20 |
2021-03-31 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
H2A.X |
canonical_H2B |
|
601_modified |
123 |
nucleosome and Gal4 complex |
Guan, R., Lian, T., Zhou, B.R., He, E., Wu, C., Singleton, M., Bai, Y. |
10.1038/s41467-021-21985-9 |
33741944 |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Xenopus laevis |
2021 |
Centromere DNA-binding protein complex CBF3 subunit B |
Nuclear division, CBF3, Centromere-associated, Kinetochore |
P40969 |
P02293, P02309, P04911, P61830 |
0.3 |
3 |
7U46 |
EM |
2.68 |
2022-03-16 |
octamer |
1 |
cenH3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
alphasat_147 |
145 |
Cryo-EM structure of CENP-A nucleosome (palindromic alpha satellite DNA) in complex with CENP-N |
Zhou, K., Gebala, M., Woods, D., Sundararajan, K., Edwards, G., Krzizike, D., Wereszczynski, J., Straight, A.F., Luger, K. |
10.1038/s41594-022-00758-y |
35422519 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2022 |
Centromere protein N |
Nuclear division, CENP-A NAC/CAD, Centromere-associated, Kinetochore |
Q96H22 |
P62807, P49450, Q93077, P62805 |
0.559 |
4 |
7U47 |
EM |
7.50 |
2022-03-16 |
octamer, octamer |
2 |
cenH3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
alphasat_147 |
145 |
CryoEM structure of CENP-N promoted nucleosome stacks with CENP-A and palindromic alpha satellite DNA sequence |
Zhou, K., Gebala, M., Woods, D., Sundararajan, K., Edwards, G., Krzizike, D., Wereszczynski, J., Straight, A.F., Luger, K. |
10.1038/s41594-022-00758-y |
35422519 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2022 |
Centromere protein N |
Nuclear division, CENP-A NAC/CAD, Centromere-associated, Kinetochore |
Q96H22 |
P62807, P49450, Q93077, P62805 |
0.179 |
5 |
7U4D |
EM |
8.10 |
2022-03-30 |
octamer, octamer |
2 |
cenH3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
139 |
CryoEM structure of CENP-N promoted nucleosome stacks with CENP-A and 601 DNA sequence |
Zhou, K., Gebala, M., Woods, D., Sundararajan, K., Edwards, G., Krzizike, D., Wereszczynski, J., Straight, A.F., Luger, K. |
10.1038/s41594-022-00758-y |
35422519 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2022 |
Centromere protein N |
Nuclear division, CENP-A NAC/CAD, Centromere-associated, Kinetochore |
Q96H22 |
P62807, P49450, Q93077, P62805 |
0.114 |
6 |
8OW0 |
EM |
3.40 |
2023-08-09 |
octamer |
1 |
cenH3 |
canonical_H4 |
H2A.X |
canonical_H2B |
|
601_modified |
121 |
Cryo-EM structure of CBF1-CCAN bound topologically to a centromeric CENP-A nucleosome |
Dendooven, T., Zhang, Z., Yang, J., McLaughlin, S.H., Schwab, J., Scheres, S.H.W., Yatskevich, S., Barford, D. |
10.1126/sciadv.adg7480 |
37506202 |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Xenopus laevis |
2023 |
Centromere-binding protein 1, Inner kinetochore subunit MCM16, Inner kinetochore subunit CTF3, Inner kinetochore subunit MCM22, Inner kinetochore subunit IML3, Inner kinetochore subunit CHL4, Inner kinetochore subunit MCM21, Inner kinetochore subunit CTF19, Inner kinetochore subunit OKP1, Inner kinetochore subunit CNN1, Inner kinetochore subunit AME1, Inner kinetochore subunit WIP1, Inner kinetochore subunit NKP1, Inner kinetochore subunit NKP2 |
Cell cycle, Transcription-associated, Centromere-associated, Nuclear division, CCAN, Kinetochore |
P17106, Q12262, Q12748, P47167, P38265, P38907, Q06675, Q02732, P53298, P43618, P38313, Q2V2P8, Q12493, Q06162 |
P02293, P02309, P04911, P36012 |
0.2 |
7 |
7BXT |
EM |
4.20 |
2021-02-10 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
145 |
The cryo-EM structure of CENP-A nucleosome in complex with CENP-C peptide and CENP-N N-terminal domain |
Ariyoshi, M., Makino, F., Watanabe, R., Nakagawa, R., Kato, T., Namba, K., Arimura, Y., Fujita, R., Kurumizaka, H., Okumura, E.I., Hara, M., Fukagawa, T. |
10.15252/embj.2020105671 |
33463726 |
Gallus gallus |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2021 |
CENP-C, Maltodextrin-binding protein,Centromere protein N |
Nuclear division, Centromere-associated, Kinetochore |
O57392, P0AEX9 |
P62805, P04908, Q16778, P84229 |
0.387 |
8 |
4X23 |
X-ray |
3.50 |
2014-12-10 |
octamer, octamer |
2 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
146 |
CRYSTAL STRUCTURE OF CENP-C IN COMPLEX WITH THE NUCLEOSOME CORE PARTICLE |
Kato, H., Jiang, J.S., Zhou, B.R., Rozendaal, M., Feng, H., Ghirlando, R., Xiao, T.S., Straight, A.F., Bai, Y. |
10.1126/science.1235532 |
23723239 |
Drosophila melanogaster |
Drosophila melanogaster |
Drosophila melanogaster |
Drosophila melanogaster |
Xenopus laevis |
2014 |
CENP-C |
Nuclear division, Centromere-associated, Kinetochore |
Q66LH7 |
P84040, P84051, P02299, P02283 |
- |
9 |
7PII |
EM |
2.68 |
2022-05-25 |
octamer |
1 |
cenH3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
|
122 |
Structure of the human CCAN CENP-A alpha-satellite complex |
Yatskevich, S., Muir, K.W., Bellini, D., Zhang, Z., Yang, J., Tischer, T., Predin, M., Dendooven, T., McLaughlin, S.H., Barford, D. |
10.1126/science.abn3810 |
35420891 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2022 |
Centromere protein C |
Nuclear division, CENP-A NAC/CAD, Centromere-associated, Kinetochore |
Q03188 |
P62807, P49450, Q93077, P62805 |
0.573 |
10 |
7YWX |
EM |
12.00 |
2022-05-18 |
octamer |
1 |
cenH3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
|
162 |
Structure of the human CCAN CENP-A alpha-satellite complex |
Yatskevich, S., Muir, K.W., Bellini, D., Zhang, Z., Yang, J., Tischer, T., Predin, M., Dendooven, T., McLaughlin, S.H., Barford, D. |
10.1126/science.abn3810 |
35420891 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2022 |
Centromere protein H, Centromere protein I, Centromere protein K, Centromere protein L, Centromere protein M, Centromere protein N, Centromere protein O, Centromere protein P, Centromere protein Q, Centromere protein R, Centromere protein S, Centromere protein T, Centromere protein U, Centromere protein W, Centromere protein X, Centromere protein C |
Fanconi anemia core complex, CENP-A NAC/CAD, DNA repair, Cell cycle, Transcription-associated, Centromere-associated, Nuclear division, Kinetochore |
Q9H3R5, Q92674, Q9BS16, Q8N0S6, Q9NSP4, Q96H22, Q9BU64, Q6IPU0, Q7L2Z9, Q13352, Q8N2Z9, Q96BT3, Q71F23, Q5EE01, A8MT69, Q03188 |
P62807, P49450, Q93077, P62805 |
0.054 |
11 |
6C0W |
EM |
4.00 |
2018-01-17 |
octamer |
1 |
cenH3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
139 |
Cryo-EM structure of human kinetochore protein CENP-N with the centromeric nucleosome containing CENP-A |
Pentakota, S., Zhou, K., Smith, C., Maffini, S., Petrovic, A., Morgan, G.P., Weir, J.R., Vetter, I.R., Musacchio, A., Luger, K. |
10.7554/eLife.33442 |
29280735 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2018 |
Centromere protein N |
Nuclear division, CENP-A NAC/CAD, Centromere-associated, Kinetochore |
Q96H22 |
P62807, P49450, Q93077, P62805 |
0.39 |
12 |
6MUP |
EM |
3.50 |
2019-07-24 |
octamer |
1 |
cenH3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
alphasat_native |
147 |
CENP-A nucleosome bound by two copies of CENP-C(CD) and two copies CENP-N(NT) |
Allu, P.K., Dawicki-McKenna, J.M., Van Eeuwen, T., Slavin, M., Braitbard, M., Xu, C., Kalisman, N., Murakami, K., Black, B.E. |
10.1016/j.cub.2019.06.062 |
31353180 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2019 |
Centromere protein C, Centromere protein N |
Nuclear division, CENP-A NAC/CAD, Centromere-associated, Kinetochore |
Q03188, Q96H22 |
P49450, Q93077, Q5QNW6, P62805 |
0.401 |
13 |
7R5R |
EM |
2.44 |
2022-04-27 |
octamer |
1 |
cenH3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
|
133 |
Structure of the human CCAN CENP-A alpha-satellite complex |
Yatskevich, S., Muir, K.W., Bellini, D., Zhang, Z., Yang, J., Tischer, T., Predin, M., Dendooven, T., McLaughlin, S.H., Barford, D. |
10.1126/science.abn3810 |
35420891 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2022 |
Centromere protein C |
Nuclear division, CENP-A NAC/CAD, Centromere-associated, Kinetochore |
Q03188 |
P62807, P49450, Q93077, P62805 |
0.571 |
14 |
6SE6 |
EM |
3.50 |
2019-08-14 |
octamer |
1 |
cenH3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
145 |
Class2 : CENP-A nucleosome in complex with CENP-C central region |
Ali-Ahmad, A., Bilokapic, S., Schafer, I.B., Halic, M., Sekulic, N. |
10.15252/embr.201948913 |
31475439 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2019 |
Centromere protein C |
Nuclear division, CENP-A NAC/CAD, Centromere-associated, Kinetochore |
Q03188 |
Q6FI13, P49450, P62807, P62805 |
0.416 |
15 |
7YYH |
EM |
8.90 |
2022-05-18 |
octamer |
1 |
cenH3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
|
153 |
Structure of the human CCANdeltaT CENP-A alpha-satellite complex |
Yatskevich, S., Muir, K.W., Bellini, D., Zhang, Z., Yang, J., Tischer, T., Predin, M., Dendooven, T., McLaughlin, S.H., Barford, D. |
10.1126/science.abn3810 |
35420891 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2022 |
Centromere protein H, Centromere protein I, Centromere protein K, Centromere protein L, Centromere protein M, Centromere protein N, Centromere protein O, Centromere protein P, Centromere protein Q, Centromere protein R, Centromere protein U, Centromere protein C |
CENP-A NAC/CAD, Cell cycle, Transcription-associated, Centromere-associated, Nuclear division, Kinetochore |
Q9H3R5, Q92674, Q9BS16, Q8N0S6, Q9NSP4, Q96H22, Q9BU64, Q6IPU0, Q7L2Z9, Q13352, Q71F23, Q03188 |
P62807, P49450, Q93077, P62805 |
0.075 |
16 |
6SEE |
EM |
4.20 |
2019-08-14 |
octamer |
1 |
cenH3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
145 |
Class2A : CENP-A nucleosome in complex with CENP-C central region |
Ali-Ahmad, A., Bilokapic, S., Schafer, I.B., Halic, M., Sekulic, N. |
10.15252/embr.201948913 |
31475439 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2019 |
Centromere protein C |
Nuclear division, CENP-A NAC/CAD, Centromere-associated, Kinetochore |
Q03188 |
Q6FI13, P49450, P62807, P62805 |
0.309 |
17 |
6SEF |
EM |
3.70 |
2019-08-14 |
octamer |
1 |
cenH3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
145 |
Class2C : CENP-A nucleosome in complex with CENP-C central region |
Ali-Ahmad, A., Bilokapic, S., Schafer, I.B., Halic, M., Sekulic, N. |
10.15252/embr.201948913 |
31475439 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2019 |
Centromere protein C |
Nuclear division, CENP-A NAC/CAD, Centromere-associated, Kinetochore |
Q03188 |
Q6FI13, P49450, P62807, P62805 |
0.372 |
18 |
7ON1 |
EM |
3.35 |
2021-07-07 |
octamer |
1 |
cenH3 |
canonical_H4 |
H2A.X |
canonical_H2B |
|
601 |
123 |
Cenp-A nucleosome in complex with Cenp-C |
Yan, K., Yang, J., Zhang, Z., Barford, D. |
|
0 |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Xenopus laevis |
2021 |
BJ4_G0006610.mRNA.1.CDS.1 |
Cell cycle, Centromere-associated, Kinetochore, Nuclear division, CCAN |
P35201 |
P02293, P02309, P04911, P36012 |
0.47 |
19 |
6MUO |
EM |
3.60 |
2019-07-24 |
octamer |
1 |
cenH3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
alphasat_native |
147 |
CENP-A nucleosome bound by two copies of CENP-C(CD) and one copy CENP-N(NT) |
Allu, P.K., Dawicki-McKenna, J.M., Van Eeuwen, T., Slavin, M., Braitbard, M., Xu, C., Kalisman, N., Murakami, K., Black, B.E. |
10.1016/j.cub.2019.06.062 |
31353180 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2019 |
Centromere protein C, Centromere protein N |
Nuclear division, CENP-A NAC/CAD, Centromere-associated, Kinetochore |
Q03188, Q96H22 |
P49450, Q93077, Q5QNW6, P62805 |
0.369 |