0 |
8TXX |
EM |
3.70 |
2024-01-17 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
147 |
Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A K15 in complex with RNF168 (Class 3) |
Hu, Q., Zhao, D., Cui, G., Bhandari, J., Thompson, J.R., Botuyan, M.V., Mer, G. |
10.1016/j.molcel.2023.12.036 |
38242129 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2024 |
E3 ubiquitin-protein ligase RNF168, Polyubiquitin-B |
Histone_ubiquitination_H2AK15_writer, Histone_ubiquitination_H2AK13_reader, Histone PTM writers, Histone_ubiquitination_H2AK15_reader, E3 ubiquitin-protein ligation, Histone PTM readers, Histone_ubiquitination_H2AK13_writer, Ubiquitin, DNA repair |
Q8IYW5, P0CG47 |
P68431, P04908, P62807, P62805 |
0.438 |
1 |
8SN3 |
EM |
3.80 |
2024-01-17 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
147 |
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A) (class 1) |
Hu, Q., Zhao, D., Cui, G., Bhandari, J., Thompson, J.R., Botuyan, M.V., Mer, G. |
10.1016/j.molcel.2023.12.036 |
38242129 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2024 |
E3 ubiquitin-protein ligase RNF168, Ubiquitin-conjugating enzyme E2 D3, Polyubiquitin-B |
Histone_ubiquitination_H2AK15_writer, Histone_ubiquitination_H2AK13_reader, Histone PTM writers, Histone_ubiquitination_H2AK15_reader, E3 ubiquitin-protein ligation, Transcription-associated, Histone PTM readers, Histone_ubiquitination_H2AK13_writer, Ubiquitin, DNA repair |
Q8IYW5, P61077, P0CG47 |
P68431, P04908, P06899, P62805 |
0.429 |
2 |
6R1U |
EM |
4.36 |
2019-04-24 |
octamer |
1 |
canonical_H3,H3.3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
147 |
Structure of LSD2/NPAC-linker/nucleosome core particle complex: Class 2 |
Marabelli, C., Marrocco, B., Pilotto, S., Chittori, S., Picaud, S., Marchese, S., Ciossani, G., Forneris, F., Filippakopoulos, P., Schoehn, G., Rhodes, D., Subramaniam, S., Mattevi, A. |
10.1016/j.celrep.2019.03.061 |
30970244 |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
2019 |
Lysine-specific histone demethylase 1B, Putative oxidoreductase GLYR1 |
Histone_methylation_H3K36_reader, Transcription-associated, Euchromatin-associated, Histone PTM readers, Histone PTM erasers, Histone_demethylation_H3K4 |
Q8NB78, Q49A26 |
P02281, P84233, P06897, P62799 |
0.198 |
3 |
8PEO |
EM |
2.69 |
2023-08-16 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
147 |
H3K36me2 nucleosome-LEDGF/p75 PWWP domain complex |
Koutna, E., Lux, V., Kouba, T., Skerlova, J., Novacek, J., Srb, P., Hexnerova, R., Svachova, H., Kukacka, Z., Novak, P., Fabry, M., Poepsel, S., Veverka, V. |
10.1093/nar/gkad674 |
37615563 |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
2023 |
PC4 and SFRS1-interacting protein |
Histone PTM readers, Transcription factors, Histone_methylation_H3K36_reader, Transcription-associated |
O75475 |
P02281, P84233, P06897, P62799 |
0.548 |
4 |
8SMW |
EM |
3.30 |
2024-01-17 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
147 |
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A. No density for Ub.) (class 1) |
Hu, Q., Zhao, D., Cui, G., Bhandari, J., Thompson, J.R., Botuyan, M.V., Mer, G. |
10.1016/j.molcel.2023.12.036 |
38242129 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2024 |
E3 ubiquitin-protein ligase RNF168, Ubiquitin-conjugating enzyme E2 D3 |
Histone_ubiquitination_H2AK15_writer, Histone_ubiquitination_H2AK13_reader, Histone PTM writers, Histone_ubiquitination_H2AK15_reader, E3 ubiquitin-protein ligation, Transcription-associated, Histone PTM readers, Histone_ubiquitination_H2AK13_writer, DNA repair |
Q8IYW5, P61077 |
P68431, P04908, P06899, P62805 |
0.526 |
5 |
8SN4 |
EM |
3.70 |
2024-01-17 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
147 |
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A) (class 2) |
Hu, Q., Zhao, D., Cui, G., Bhandari, J., Thompson, J.R., Botuyan, M.V., Mer, G. |
10.1016/j.molcel.2023.12.036 |
38242129 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2024 |
E3 ubiquitin-protein ligase RNF168, Ubiquitin-conjugating enzyme E2 D3, Polyubiquitin-B |
Histone_ubiquitination_H2AK15_writer, Histone_ubiquitination_H2AK13_reader, Histone PTM writers, Histone_ubiquitination_H2AK15_reader, E3 ubiquitin-protein ligation, Transcription-associated, Histone PTM readers, Histone_ubiquitination_H2AK13_writer, Ubiquitin, DNA repair |
Q8IYW5, P61077, P0CG47 |
P68431, P04908, P06899, P62805 |
0.439 |
6 |
8SN5 |
EM |
3.90 |
2024-01-17 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
147 |
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A) (class 3) |
Hu, Q., Zhao, D., Cui, G., Bhandari, J., Thompson, J.R., Botuyan, M.V., Mer, G. |
10.1016/j.molcel.2023.12.036 |
38242129 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2024 |
E3 ubiquitin-protein ligase RNF168, Ubiquitin-conjugating enzyme E2 D3, Polyubiquitin-B |
Histone_ubiquitination_H2AK15_writer, Histone_ubiquitination_H2AK13_reader, Histone PTM writers, Histone_ubiquitination_H2AK15_reader, E3 ubiquitin-protein ligation, Transcription-associated, Histone PTM readers, Histone_ubiquitination_H2AK13_writer, Ubiquitin, DNA repair |
Q8IYW5, P61077, P0CG47 |
P68431, P04908, P06899, P62805 |
0.41 |
7 |
8SN6 |
EM |
3.70 |
2024-01-17 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
147 |
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A) (class 4) |
Hu, Q., Zhao, D., Cui, G., Bhandari, J., Thompson, J.R., Botuyan, M.V., Mer, G. |
10.1016/j.molcel.2023.12.036 |
38242129 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2024 |
E3 ubiquitin-protein ligase RNF168, Ubiquitin-conjugating enzyme E2 D3, Polyubiquitin-B |
Histone_ubiquitination_H2AK15_writer, Histone_ubiquitination_H2AK13_reader, Histone PTM writers, Histone_ubiquitination_H2AK15_reader, E3 ubiquitin-protein ligation, Transcription-associated, Histone PTM readers, Histone_ubiquitination_H2AK13_writer, Ubiquitin, DNA repair |
Q8IYW5, P61077, P0CG47 |
P68431, P04908, P06899, P62805 |
0.434 |
8 |
8SNA |
EM |
4.00 |
2024-01-17 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
147 |
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c with backside ubiquitin (UbcH5c chemically conjugated to histone H2A) (class 2) |
Hu, Q., Zhao, D., Cui, G., Bhandari, J., Thompson, J.R., Botuyan, M.V., Mer, G. |
10.1016/j.molcel.2023.12.036 |
38242129 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2024 |
E3 ubiquitin-protein ligase RNF168, Ubiquitin-conjugating enzyme E2 D3, Polyubiquitin-B |
Histone_ubiquitination_H2AK15_writer, Histone_ubiquitination_H2AK13_reader, Histone PTM writers, Histone_ubiquitination_H2AK15_reader, E3 ubiquitin-protein ligation, Transcription-associated, Histone PTM readers, Histone_ubiquitination_H2AK13_writer, Ubiquitin, DNA repair |
Q8IYW5, P61077, P0CG47 |
P68431, P04908, P06899, P62805 |
0.405 |
9 |
9DDE |
EM |
3.20 |
2024-11-20 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
H1.4 |
601 |
162 |
ncPRC1RYBP bound to H2AK119Ub/H1.4 chromatosome |
Lopez, V.G., Valencia-Sanchez, M.I., Abini-Agbomson, S., Thomas, J.F., Lee, R., De Ioannes, P., Sosa, B.A., Armache, J.P., Armache, K.J. |
10.1038/s41586-024-08183-5 |
39537923 |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
Homo sapiens |
2024 |
Polycomb complex protein BMI-1, E3 ubiquitin-protein ligase RING2, RING1 and YY1-binding protein, Ubiquitin |
Histone PTM writers, Histone_ubiquitination_H2AK119_writer, Polycomb, Transcription-associated, E3 ubiquitin-protein ligation, Heterochromatin-associated, Histone_methylation_H3K27_writer, Histone PTM readers, Histone_ubiquitination_reader, Ubiquitin |
P35226, Q99496, Q8N488, P0CG48 |
P84233, P06897, P10412, P62799, P02281 |
0.456 |
10 |
9IPU |
EM |
4.30 |
2024-10-02 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
H1.0 |
601L |
170 |
cryo-EM structure of the RNF168(1-193)/UbcH5c-Ub ubiquitylation module bound to H1.0-K63-Ub3 modified chromatosome |
Shi, Q., Deng, Z., Zhang, L., Tong, Z., Li, J.B., Chu, G.C., Ai, H., Liu, L. |
10.1002/anie.202413651 |
39363740 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
2024 |
Ubiquitin-conjugating enzyme E2 D3, E3 ubiquitin-protein ligase RNF168, Ubiquitin |
Histone_ubiquitination_H2AK15_writer, Histone_ubiquitination_H2AK13_reader, Histone PTM writers, Histone_ubiquitination_H2AK15_reader, Transcription-associated, E3 ubiquitin-protein ligation, Histone PTM readers, Histone_ubiquitination_H2AK13_writer, Ubiquitin, DNA repair |
P61077, Q8IYW5, P62979 |
Q71DI3, P04908, P07305, P62805, O60814 |
0.237 |
11 |
8X19 |
EM |
3.20 |
2024-03-06 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
147 |
Structure of nucleosome-bound SRCAP-C in the ADP-BeFx-bound state |
Yu, J., Sui, F., Gu, F., Li, W., Yu, Z., Wang, Q., He, S., Wang, L., Xu, Y. |
10.1038/s41421-023-00640-1 |
38331872 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2024 |
Helicase SRCAP, Vacuolar protein sorting-associated protein 72 homolog, Actin-related protein 6, Zinc finger HIT domain-containing protein 1, RuvB-like 1, RuvB-like 2, Actin, cytoplasmic 1, Actin-like protein 6A, DNA methyltransferase 1-associated protein 1, YEATS domain-containing protein 4 |
INO80, SRCAP (INO80), Chromatin remodelers, Histone_acetylation_reader, Histone chaperones, Cell cycle, Euchromatin-associated, Transcription-associated, Histone PTM readers |
Q6ZRS2, Q15906, Q9GZN1, O43257, Q9Y265, Q9Y230, P60709, O96019, Q9NPF5, O95619 |
P62807, P68431, Q93077, P62805 |
0.292 |
12 |
8CBN |
EM |
3.34 |
2023-12-27 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
150 |
structure of LEDGF/p75 PWWP domain bound to the H3K36 trimethylated dinucleosome |
Koutna, E., Lux, V., Kouba, T., Skerlova, J., Novacek, J., Srb, P., Hexnerova, R., Svachova, H., Kukacka, Z., Novak, P., Fabry, M., Poepsel, S., Veverka, V. |
10.1093/nar/gkad674 |
37615563 |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
2023 |
PC4 and SFRS1-interacting protein |
Histone PTM readers, Transcription factors, Histone_methylation_H3K36_reader, Transcription-associated |
O75475 |
P02281, P84233, P06897, P62799 |
0.392 |
13 |
8CBQ |
EM |
4.00 |
2023-09-06 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
150 |
structure of LEDGF/p75 PWWP domain bound to the H3K36 trimethylated dinucleosome |
Koutna, E., Lux, V., Kouba, T., Skerlova, J., Novacek, J., Srb, P., Hexnerova, R., Svachova, H., Kukacka, Z., Novak, P., Fabry, M., Poepsel, S., Veverka, V. |
10.1093/nar/gkad674 |
37615563 |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
2023 |
PC4 and SFRS1-interacting protein |
Histone PTM readers, Transcription factors, Histone_methylation_H3K36_reader, Transcription-associated |
O75475 |
P02281, P84233, P06897, P62799 |
0.304 |
14 |
8PC5 |
EM |
3.02 |
2023-08-16 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
147 |
H3K36me3 nucleosome-LEDGF/p75 PWWP domain complex |
Koutna, E., Lux, V., Kouba, T., Skerlova, J., Novacek, J., Srb, P., Hexnerova, R., Svachova, H., Kukacka, Z., Novak, P., Fabry, M., Poepsel, S., Veverka, V. |
10.1093/nar/gkad674 |
37615563 |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
2023 |
PC4 and SFRS1-interacting protein |
Histone PTM readers, Transcription factors, Histone_methylation_H3K36_reader, Transcription-associated |
O75475 |
P02281, P84233, P06897, P62799 |
0.521 |
15 |
8PP6 |
EM |
3.18 |
2024-04-03 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
156 |
human RYBP-PRC1 bound to H2AK118ub1 nucleosome |
Ciapponi, M., Karlukova, E., Schkolziger, S., Benda, C., Muller, J. |
10.1038/s41594-024-01258-x |
38528151 |
Drosophila melanogaster |
Drosophila melanogaster |
Drosophila melanogaster |
Drosophila melanogaster |
Xenopus laevis |
2024 |
RING1 and YY1-binding protein, Ubiquitin-40S ribosomal protein S27a (Fragment) |
Polycomb, Histone_ubiquitination_reader, Transcription-associated, Histone PTM readers, Heterochromatin-associated, Ubiquitin |
Q8N488, P0CG47 |
P84040, P84051, P02299, P02283 |
0.465 |
16 |
8SN7 |
EM |
3.70 |
2024-01-17 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
147 |
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A) (class 5) |
Hu, Q., Zhao, D., Cui, G., Bhandari, J., Thompson, J.R., Botuyan, M.V., Mer, G. |
10.1016/j.molcel.2023.12.036 |
38242129 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2024 |
E3 ubiquitin-protein ligase RNF168, Ubiquitin-conjugating enzyme E2 D3, Polyubiquitin-B |
Histone_ubiquitination_H2AK15_writer, Histone_ubiquitination_H2AK13_reader, Histone PTM writers, Histone_ubiquitination_H2AK15_reader, E3 ubiquitin-protein ligation, Transcription-associated, Histone PTM readers, Histone_ubiquitination_H2AK13_writer, Ubiquitin, DNA repair |
Q8IYW5, P61077, P0CG47 |
P68431, P04908, P06899, P62805 |
0.445 |
17 |
8U13 |
EM |
3.80 |
2024-01-17 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
147 |
Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A lysine 15 in complex with RNF168-UbcH5c (class 1) |
Hu, Q., Zhao, D., Cui, G., Bhandari, J., Thompson, J.R., Botuyan, M.V., Mer, G. |
10.1016/j.molcel.2023.12.036 |
38242129 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2024 |
E3 ubiquitin-protein ligase RNF168 |
Histone_ubiquitination_H2AK15_writer, Histone_ubiquitination_H2AK13_reader, Histone PTM writers, Histone_ubiquitination_H2AK15_reader, E3 ubiquitin-protein ligation, Histone PTM readers, Histone_ubiquitination_H2AK13_writer, DNA repair |
Q8IYW5 |
P68431, P04908, P62807, P62805 |
0.381 |
18 |
8X15 |
EM |
3.20 |
2024-03-06 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
137 |
Structure of nucleosome-bound SRCAP-C in the apo state |
Yu, J., Sui, F., Gu, F., Li, W., Yu, Z., Wang, Q., He, S., Wang, L., Xu, Y. |
10.1038/s41421-023-00640-1 |
38331872 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2024 |
Helicase SRCAP, Vacuolar protein sorting-associated protein 72 homolog, Actin-related protein 6, Zinc finger HIT domain-containing protein 1, RuvB-like 1, RuvB-like 2, Actin, cytoplasmic 1, N-terminally processed, Actin-like protein 6A, DNA methyltransferase 1-associated protein 1, YEATS domain-containing protein 4 |
INO80, SRCAP (INO80), Chromatin remodelers, Histone_acetylation_reader, Histone chaperones, Cell cycle, Euchromatin-associated, Transcription-associated, Histone PTM readers |
Q6ZRS2, Q15906, Q9GZN1, O43257, Q9Y265, Q9Y230, P60709, O96019, Q9NPF5, O95619 |
P62807, P68431, Q93077, P62805 |
0.218 |
19 |
5KGF |
EM |
4.54 |
2016-07-27 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
145 |
Structural model of 53BP1 bound to a ubiquitylated and methylated nucleosome, at 4.5 A resolution |
Wilson, M.D., Benlekbir, S., Fradet-Turcotte, A., Sherker, A., Julien, J.P., McEwan, A., Noordermeer, S.M., Sicheri, F., Rubinstein, J.L., Durocher, D. |
10.1038/nature18951 |
27462807 |
Xenopus laevis |
Xenopus laevis |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2016 |
Tumor suppressor p53-binding protein 1, Ubiquitin |
Histone_ubiquitination_H2AK15_reader, Telomere-associated, Histone PTM readers, Ubiquitin, DNA repair, Histone_methylation_H4K20_reader |
Q12888, P0CG47 |
P0C0S8, P84233, P62807, P62799 |
0.301 |
20 |
8UPF |
EM |
3.20 |
2024-01-17 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
147 |
Cryo-EM structure of the human nucleosome core particle in complex with RNF168-UbcH5c |
Hu, Q., Zhao, D., Cui, G., Bhandari, J., Thompson, J.R., Botuyan, M.V., Mer, G. |
10.1016/j.molcel.2023.12.036 |
38242129 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2024 |
E3 ubiquitin-protein ligase RNF168, Ubiquitin-conjugating enzyme E2 D3 |
Histone_ubiquitination_H2AK15_writer, Histone_ubiquitination_H2AK13_reader, Histone PTM writers, Histone_ubiquitination_H2AK15_reader, E3 ubiquitin-protein ligation, Transcription-associated, Histone PTM readers, Histone_ubiquitination_H2AK13_writer, DNA repair |
Q8IYW5, P61077 |
P68431, P04908, P06899, P62805 |
0.464 |
21 |
8X7K |
EM |
3.27 |
2024-08-07 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
143 |
Cryo-EM structures of RNF168/UbcH5c-Ub in complex with H2AK13Ub nucleosomes determined by activity-based chemical trapping strategy (adjacent H2AK13/15 dual-monoubiquitination) |
Ai, H., Tong, Z., Deng, Z., Shi, Q., Tao, S., Liang, J., Sun, M., Wu, X., Zheng, Q., Liang, L., Li, J.B., Gao, S., Tian, C., Liu, L., Pan, M. |
10.1101/2024.01.02.573964 |
0 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2024 |
Ubiquitin-conjugating enzyme E2 D3, E3 ubiquitin-protein ligase RNF168 |
Histone_ubiquitination_H2AK15_writer, Histone_ubiquitination_H2AK13_reader, Histone PTM writers, Histone_ubiquitination_H2AK15_reader, Transcription-associated, E3 ubiquitin-protein ligation, Histone PTM readers, Histone_ubiquitination_H2AK13_writer, DNA repair |
P61077, Q8IYW5 |
O60814, P04908, Q71DI3, P62805 |
0.423 |
22 |
8X7J |
EM |
3.39 |
2024-08-07 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
144 |
Cryo-EM structures of RNF168/UbcH5c-Ub/nucleosomes complex determined by activity-based chemical trapping strategy |
Ai, H., Tong, Z., Deng, Z., Shi, Q., Tao, S., Liang, J., Sun, M., Wu, X., Zheng, Q., Liang, L., Li, J.B., Gao, S., Tian, C., Liu, L., Pan, M. |
10.1101/2024.01.02.573964 |
0 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2024 |
Ubiquitin-conjugating enzyme E2 D3, E3 ubiquitin-protein ligase RNF168, Ubiquitin |
Histone_ubiquitination_H2AK15_writer, Histone_ubiquitination_H2AK13_reader, Histone PTM writers, Histone_ubiquitination_H2AK15_reader, Transcription-associated, E3 ubiquitin-protein ligation, Histone PTM readers, Histone_ubiquitination_H2AK13_writer, Ubiquitin, DNA repair |
P61077, Q8IYW5, P62979 |
O60814, P04908, Q71DI3, P62805 |
0.391 |
23 |
8HR1 |
EM |
3.02 |
2023-09-13 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
147 |
Cryo-EM structure of SSX1 bound to the unmodified nucleosome at a resolution of 3.02 angstrom |
Tong, Z., Ai, H., Xu, Z., He, K., Chu, G.C., Shi, Q., Deng, Z., Xue, Q., Sun, M., Du, Y., Liang, L., Li, J.B., Pan, M., Liu, L. |
10.1038/s41594-023-01141-1 |
38177667 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2023 |
SSX1 |
Histone_ubiquitination_H2AK119_reader, Histone PTM readers, Transcription-associated |
Q16384 |
O60814, P04908, Q71DI3, P62805 |
0.532 |
24 |
8SN8 |
EM |
3.70 |
2024-01-17 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
147 |
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A) (class 6) |
Hu, Q., Zhao, D., Cui, G., Bhandari, J., Thompson, J.R., Botuyan, M.V., Mer, G. |
10.1016/j.molcel.2023.12.036 |
38242129 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2024 |
E3 ubiquitin-protein ligase RNF168, Ubiquitin-conjugating enzyme E2 D3, Polyubiquitin-B |
Histone_ubiquitination_H2AK15_writer, Histone_ubiquitination_H2AK13_reader, Histone PTM writers, Histone_ubiquitination_H2AK15_reader, E3 ubiquitin-protein ligation, Transcription-associated, Histone PTM readers, Histone_ubiquitination_H2AK13_writer, Ubiquitin, DNA repair |
Q8IYW5, P61077, P0CG47 |
P68431, P04908, P06899, P62805 |
0.443 |
25 |
8SN9 |
EM |
3.90 |
2024-01-17 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
147 |
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c with backside ubiquitin (UbcH5c chemically conjugated to histone H2A) (class 1) |
Hu, Q., Zhao, D., Cui, G., Bhandari, J., Thompson, J.R., Botuyan, M.V., Mer, G. |
10.1016/j.molcel.2023.12.036 |
38242129 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2024 |
E3 ubiquitin-protein ligase RNF168, Ubiquitin-conjugating enzyme E2 D3, Polyubiquitin-B |
Histone_ubiquitination_H2AK15_writer, Histone_ubiquitination_H2AK13_reader, Histone PTM writers, Histone_ubiquitination_H2AK15_reader, E3 ubiquitin-protein ligation, Transcription-associated, Histone PTM readers, Histone_ubiquitination_H2AK13_writer, Ubiquitin, DNA repair |
Q8IYW5, P61077, P0CG47 |
P68431, P04908, P06899, P62805 |
0.424 |
26 |
8TXW |
EM |
3.60 |
2024-01-17 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
147 |
Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A K15 in complex with RNF168 (Class 2) |
Hu, Q., Zhao, D., Cui, G., Bhandari, J., Thompson, J.R., Botuyan, M.V., Mer, G. |
10.1016/j.molcel.2023.12.036 |
38242129 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2024 |
E3 ubiquitin-protein ligase RNF168, Polyubiquitin-B |
Histone_ubiquitination_H2AK15_writer, Histone_ubiquitination_H2AK13_reader, Histone PTM writers, Histone_ubiquitination_H2AK15_reader, E3 ubiquitin-protein ligation, Histone PTM readers, Histone_ubiquitination_H2AK13_writer, Ubiquitin, DNA repair |
Q8IYW5, P0CG47 |
P68431, P04908, P62807, P62805 |
0.455 |
27 |
8X1C |
EM |
3.20 |
2024-03-06 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
147 |
Structure of nucleosome-bound SRCAP-C in the ADP-bound state |
Yu, J., Sui, F., Gu, F., Li, W., Yu, Z., Wang, Q., He, S., Wang, L., Xu, Y. |
10.1038/s41421-023-00640-1 |
38331872 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2024 |
Helicase SRCAP, Vacuolar protein sorting-associated protein 72 homolog, Actin-related protein 6, Zinc finger HIT domain-containing protein 1, RuvB-like 1, RuvB-like 2, Actin, cytoplasmic 1, Actin-like protein 6A, DNA methyltransferase 1-associated protein 1, YEATS domain-containing protein 4 |
INO80, SRCAP (INO80), Chromatin remodelers, Histone_acetylation_reader, Histone chaperones, Cell cycle, Euchromatin-associated, Transcription-associated, Histone PTM readers |
Q6ZRS2, Q15906, Q9GZN1, O43257, Q9Y265, Q9Y230, P60709, O96019, Q9NPF5, O95619 |
P62807, P68431, Q93077, P62805 |
0.297 |
28 |
9DBY |
EM |
2.80 |
2024-11-20 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
148 |
ncPRC1RYBP bound to singly modified H2AK119Ub nucleosome |
Lopez, V.G., Valencia-Sanchez, M.I., Abini-Agbomson, S., Thomas, J.F., Lee, R., De Ioannes, P., Sosa, B.A., Armache, J.P., Armache, K.J. |
10.1038/s41586-024-08183-5 |
39537923 |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
2024 |
Polycomb complex protein BMI-1, E3 ubiquitin-protein ligase RING2, RING1 and YY1-binding protein, Ubiquitin |
Histone PTM writers, Histone_ubiquitination_H2AK119_writer, Polycomb, Transcription-associated, E3 ubiquitin-protein ligation, Heterochromatin-associated, Histone_methylation_H3K27_writer, Histone PTM readers, Histone_ubiquitination_reader, Ubiquitin |
P35226, Q99496, Q8N488, P0CG48 |
P02281, P84233, P06897, P62799 |
0.39 |
29 |
9DG3 |
EM |
3.46 |
2024-11-20 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
146 |
ncPRC1RYBP Delta-linker mutant bound to singly modified H2AK119Ub nucleosome |
Lopez, V.G., Valencia-Sanchez, M.I., Abini-Agbomson, S., Thomas, J.F., Lee, R., De Ioannes, P., Sosa, B.A., Armache, J.P., Armache, K.J. |
10.1038/s41586-024-08183-5 |
39537923 |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
2024 |
RING1 and YY1-binding protein, Ubiquitin |
Polycomb, Histone_ubiquitination_reader, Transcription-associated, Histone PTM readers, Heterochromatin-associated, Ubiquitin |
Q8N488, P0CG48 |
P02281, P84233, P06897, P62799 |
0.382 |
30 |
7YQK |
EM |
3.38 |
2022-08-17 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
H2A.X |
canonical_H2B |
|
601 |
145 |
cryo-EM structure of gammaH2AXK15ub-H4K20me2 nucleosome bound to 53BP1 |
Ai, H., Chu, G.C., Gong, Q., Tong, Z.B., Deng, Z., Liu, X., Yang, F., Xu, Z., Li, J.B., Tian, C., Liu, L. |
10.1021/jacs.2c06156 |
36166692 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2022 |
UDR motif of 53BP1, TP53-binding protein 1, Polyubiquitin-B |
Histone_ubiquitination_H2AK15_reader, Telomere-associated, Histone PTM readers, Ubiquitin, DNA repair, Histone_methylation_H4K20_reader |
Q12888, P0CG47 |
P16104, O60814, P68431, P62805 |
0.424 |
31 |
8PC6 |
EM |
3.04 |
2023-08-16 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
147 |
H3K36me3 nucleosome-LEDGF/p75 PWWP domain complex - pose 2 |
Koutna, E., Lux, V., Kouba, T., Skerlova, J., Novacek, J., Srb, P., Hexnerova, R., Svachova, H., Kukacka, Z., Novak, P., Fabry, M., Poepsel, S., Veverka, V. |
10.1093/nar/gkad674 |
37615563 |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
2023 |
PC4 and SFRS1-interacting protein |
Histone PTM readers, Transcription factors, Histone_methylation_H3K36_reader, Transcription-associated |
O75475 |
P02281, P84233, P06897, P62799 |
0.484 |
32 |
8SMY |
EM |
3.20 |
2024-01-17 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
147 |
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A. No density for Ub.) (class 3) |
Hu, Q., Zhao, D., Cui, G., Bhandari, J., Thompson, J.R., Botuyan, M.V., Mer, G. |
10.1016/j.molcel.2023.12.036 |
38242129 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2024 |
E3 ubiquitin-protein ligase RNF168, Ubiquitin-conjugating enzyme E2 D3 |
Histone_ubiquitination_H2AK15_writer, Histone_ubiquitination_H2AK13_reader, Histone PTM writers, Histone_ubiquitination_H2AK15_reader, E3 ubiquitin-protein ligation, Transcription-associated, Histone PTM readers, Histone_ubiquitination_H2AK13_writer, DNA repair |
Q8IYW5, P61077 |
P68431, P04908, P06899, P62805 |
0.544 |
33 |
8TXV |
EM |
3.80 |
2024-01-17 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
147 |
Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A K15 in complex with RNF168 (Class 1) |
Hu, Q., Zhao, D., Cui, G., Bhandari, J., Thompson, J.R., Botuyan, M.V., Mer, G. |
10.1016/j.molcel.2023.12.036 |
38242129 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2024 |
E3 ubiquitin-protein ligase RNF168, Polyubiquitin-B |
Histone_ubiquitination_H2AK15_writer, Histone_ubiquitination_H2AK13_reader, Histone PTM writers, Histone_ubiquitination_H2AK15_reader, E3 ubiquitin-protein ligation, Histone PTM readers, Histone_ubiquitination_H2AK13_writer, Ubiquitin, DNA repair |
Q8IYW5, P0CG47 |
P68431, P04908, P62807, P62805 |
0.432 |
34 |
8U14 |
EM |
3.90 |
2024-01-17 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
147 |
Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A lysine 15 in complex with RNF168-UbcH5c (class 2) |
Hu, Q., Zhao, D., Cui, G., Bhandari, J., Thompson, J.R., Botuyan, M.V., Mer, G. |
10.1016/j.molcel.2023.12.036 |
38242129 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2024 |
E3 ubiquitin-protein ligase RNF168, Ubiquitin-conjugating enzyme E2 D3 |
Histone_ubiquitination_H2AK15_writer, Histone_ubiquitination_H2AK13_reader, Histone PTM writers, Histone_ubiquitination_H2AK15_reader, E3 ubiquitin-protein ligation, Transcription-associated, Histone PTM readers, Histone_ubiquitination_H2AK13_writer, DNA repair |
Q8IYW5, P61077 |
P68431, P04908, P06899, P62805 |
0.352 |
35 |
6S01 |
EM |
3.20 |
2019-12-18 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
150 |
Structure of LEDGF PWWP domain bound H3K36 methylated nucleosome |
Wang, H., Farnung, L., Dienemann, C., Cramer, P. |
10.1038/s41594-019-0345-4 |
31819277 |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
2019 |
PC4 and SFRS1-interacting protein |
Histone PTM readers, Transcription factors, Histone_methylation_H3K36_reader, Transcription-associated |
O75475 |
P02281, P84233, P06897, P62799 |
0.529 |
36 |
8HQY |
EM |
3.05 |
2023-09-27 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
136 |
Cryo-EM structure of SSX1 bound to the H2AK119Ub nucleosome at a resolution of 3.05 angstrom |
Tong, Z., Ai, H., Xu, Z., He, K., Chu, G.C., Shi, Q., Deng, Z., Xue, Q., Sun, M., Du, Y., Liang, L., Li, J.B., Pan, M., Liu, L. |
10.1038/s41594-023-01141-1 |
38177667 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2023 |
Protein SSX2, Polyubiquitin-B (Fragment) |
Histone_ubiquitination_H2AK119_reader, Histone PTM readers, Ubiquitin, Transcription-associated |
Q16385, P0CG47 |
O60814, P04908, Q71DI3, P62805 |
0.47 |
37 |
8SMX |
EM |
3.20 |
2024-01-17 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
147 |
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A. No density for Ub.) (class 2) |
Hu, Q., Zhao, D., Cui, G., Bhandari, J., Thompson, J.R., Botuyan, M.V., Mer, G. |
10.1016/j.molcel.2023.12.036 |
38242129 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2024 |
E3 ubiquitin-protein ligase RNF168, Ubiquitin-conjugating enzyme E2 D3 |
Histone_ubiquitination_H2AK15_writer, Histone_ubiquitination_H2AK13_reader, Histone PTM writers, Histone_ubiquitination_H2AK15_reader, E3 ubiquitin-protein ligation, Transcription-associated, Histone PTM readers, Histone_ubiquitination_H2AK13_writer, DNA repair |
Q8IYW5, P61077 |
P68431, P04908, P06899, P62805 |
0.549 |
38 |
8SMZ |
EM |
3.20 |
2024-01-17 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
147 |
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A. No density for Ub.) (Class 4) |
Hu, Q., Zhao, D., Cui, G., Bhandari, J., Thompson, J.R., Botuyan, M.V., Mer, G. |
10.1016/j.molcel.2023.12.036 |
38242129 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2024 |
E3 ubiquitin-protein ligase RNF168, Ubiquitin-conjugating enzyme E2 D3 |
Histone_ubiquitination_H2AK15_writer, Histone_ubiquitination_H2AK13_reader, Histone PTM writers, Histone_ubiquitination_H2AK15_reader, E3 ubiquitin-protein ligation, Transcription-associated, Histone PTM readers, Histone_ubiquitination_H2AK13_writer, DNA repair |
Q8IYW5, P61077 |
P68431, P04908, P06899, P62805 |
0.535 |
39 |
8SN1 |
EM |
3.30 |
2024-01-17 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
147 |
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A. No density for Ub.) (class 6) |
Hu, Q., Zhao, D., Cui, G., Bhandari, J., Thompson, J.R., Botuyan, M.V., Mer, G. |
10.1016/j.molcel.2023.12.036 |
38242129 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2024 |
E3 ubiquitin-protein ligase RNF168, Ubiquitin-conjugating enzyme E2 D3 |
Histone_ubiquitination_H2AK15_writer, Histone_ubiquitination_H2AK13_reader, Histone PTM writers, Histone_ubiquitination_H2AK15_reader, E3 ubiquitin-protein ligation, Transcription-associated, Histone PTM readers, Histone_ubiquitination_H2AK13_writer, DNA repair |
Q8IYW5, P61077 |
P68431, P04908, P06899, P62805 |
0.526 |
40 |
8X7I |
EM |
3.27 |
2024-08-07 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
147 |
Cryo-EM structures of RNF168/UbcH5c-Ub in complex with H2AK13Ub nucleosomes determined by intein-based E2-Ub-NCP conjugation strategy |
Ai, H., Tong, Z., Deng, Z., Shi, Q., Tao, S., Liang, J., Sun, M., Wu, X., Zheng, Q., Liang, L., Li, J.B., Gao, S., Tian, C., Liu, L., Pan, M. |
10.1101/2024.01.02.573964 |
0 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2024 |
Ubiquitin-conjugating enzyme E2 D3, E3 ubiquitin-protein ligase RNF168, Ubiquitin |
Histone_ubiquitination_H2AK15_writer, Histone_ubiquitination_H2AK13_reader, Histone PTM writers, Histone_ubiquitination_H2AK15_reader, Transcription-associated, E3 ubiquitin-protein ligation, Histone PTM readers, Histone_ubiquitination_H2AK13_writer, Ubiquitin, DNA repair |
P61077, Q8IYW5, P62979 |
O60814, P04908, Q71DI3, P62805 |
0.443 |
41 |
6R25 |
EM |
4.61 |
2019-04-24 |
octamer |
1 |
canonical_H3,H3.3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
147 |
Structure of LSD2/NPAC-linker/nucleosome core particle complex: Class 3 |
Marabelli, C., Marrocco, B., Pilotto, S., Chittori, S., Picaud, S., Marchese, S., Ciossani, G., Forneris, F., Filippakopoulos, P., Schoehn, G., Rhodes, D., Subramaniam, S., Mattevi, A. |
10.1016/j.celrep.2019.03.061 |
30970244 |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
2019 |
Lysine-specific histone demethylase 1B, NPAC |
Histone_methylation_H3K36_reader, Transcription-associated, Euchromatin-associated, Histone PTM readers, Histone PTM erasers, Histone_demethylation_H3K4 |
Q8NB78, Q49A26 |
P02281, P84233, P06897, P62799 |
0.186 |
42 |
8SN2 |
EM |
3.60 |
2024-01-17 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
147 |
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c (UbcH5c chemically conjugated to histone H2A) |
Hu, Q., Zhao, D., Cui, G., Bhandari, J., Thompson, J.R., Botuyan, M.V., Mer, G. |
10.1016/j.molcel.2023.12.036 |
38242129 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2024 |
E3 ubiquitin-protein ligase RNF168, Ubiquitin-conjugating enzyme E2 D3 |
Histone_ubiquitination_H2AK15_writer, Histone_ubiquitination_H2AK13_reader, Histone PTM writers, Histone_ubiquitination_H2AK15_reader, E3 ubiquitin-protein ligation, Transcription-associated, Histone PTM readers, Histone_ubiquitination_H2AK13_writer, DNA repair |
Q8IYW5, P61077 |
P68431, P04908, P06899, P62805 |
0.452 |
43 |
8UXQ |
EM |
6.30 |
2024-09-25 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
H2A.Z |
canonical_H2B |
|
601 |
97 |
Structure of Heterochromatin Protein 1 (HP1) alpha in complex with an H2A.Z nucleosome |
Sokolova, V., Miratsky, J., Svetlov, V., Brenowitz, M., Vant, J., Lewis, T.S., Dryden, K., Lee, G., Sarkar, S., Nudler, E., Singharoy, A., Tan, D. |
10.1016/j.str.2024.09.013 |
39383876 |
Xenopus laevis |
Xenopus laevis |
Mus musculus |
Xenopus laevis |
Xenopus laevis |
2024 |
Chromobox protein homolog 5 |
Histone_methylation_H3K9_reader, Histone PTM readers, Heterochromatin-associated, Transcription-associated |
P45973 |
P02281, P84233, P0C0S6, P62799 |
0.143 |
44 |
8SN0 |
EM |
3.20 |
2024-01-17 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
147 |
Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A. No density for Ub.) (class 5) |
Hu, Q., Zhao, D., Cui, G., Bhandari, J., Thompson, J.R., Botuyan, M.V., Mer, G. |
10.1016/j.molcel.2023.12.036 |
38242129 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2024 |
E3 ubiquitin-protein ligase RNF168, Ubiquitin-conjugating enzyme E2 D3 |
Histone_ubiquitination_H2AK15_writer, Histone_ubiquitination_H2AK13_reader, Histone PTM writers, Histone_ubiquitination_H2AK15_reader, E3 ubiquitin-protein ligation, Transcription-associated, Histone PTM readers, Histone_ubiquitination_H2AK13_writer, DNA repair |
Q8IYW5, P61077 |
P68431, P04908, P06899, P62805 |
0.547 |
45 |
8PEP |
EM |
3.33 |
2023-08-16 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
147 |
H3K36me2 nucleosome-LEDGF/p75 PWWP domain complex - pose 2 |
Koutna, E., Lux, V., Kouba, T., Skerlova, J., Novacek, J., Srb, P., Hexnerova, R., Svachova, H., Kukacka, Z., Novak, P., Fabry, M., Poepsel, S., Veverka, V. |
10.1093/nar/gkad674 |
37615563 |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
2023 |
PC4 and SFRS1-interacting protein |
Histone PTM readers, Transcription factors, Histone_methylation_H3K36_reader, Transcription-associated |
O75475 |
P02281, P84233, P06897, P62799 |
0.399 |