| 0 |
7XSX |
EM |
3.8 |
2022-09-07 |
octamer |
1 |
H3.3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601_modified |
108 |
RNA polymerase II elongation complex transcribing a nucleosome (EC49) |
Ehara, H., Kujirai, T., Shirouzu, M., Kurumizaka, H., Sekine, S.I. |
10.1126/science.abp9466 |
35981082 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
|
2022 |
DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, RNA polymerase II third largest subunit B44, part of central core, RNA polymerase II subunit B32, DNA-directed RNA polymerases I, II, and III subunit RPABC1, RNA polymerase subunit ABC23, common to RNA polymerases I, II, and III, RNA polymerase II subunit, DNA-directed RNA polymerases I, II, and III subunit RPABC3, RNA polymerase subunit ABC10-beta, common to RNA polymerases I, II, and III, RNA polymerase II subunit B12.5, RNA polymerase subunit ABC10-alpha, Transcription elongation factor 1 homolog, Transcription elongation factor SPT4, Transcription elongation factor SPT5, FACT complex subunit, FACT complex subunit POB3, Transcription elongation factor Spt6, Protein that interacts with Spt6p and copurifies with Spt5p and RNA polymerase II, Component of the Paf1p complex, RNAPII-associated chromatin remodeling Paf1 complex subunit, Leo1, RNAP II-associated protein, Constituent of Paf1 complex with RNA polymerase II, Paf1p, Hpr1p, Ctr9, Leo1, Rtf1 and Ccr4p |
Histone chaperones, RNA polymerases, FACT, DNA repair, Transcription factors, DNA replication, Transcription-associated, SPT4-SPT5 complex |
C4R4Y0, C4QZQ7, C4R7L2, C4R2U9, C4R3P8, C4R1V1, C4R9A1, C4R273, F2QPE6, C4R009, C4R3Z5, F2QMI1, C4QZ45, C4R0E6, C4R370, C4QYQ8, F2QNN8, C4R7H2, C4R7L8, C4R6B2, F2QQ42, C4R3K1, C4R997, C4R1E6 |
P62805, P06899, P84243, P04908 |
0.227 |
| 1 |
7XT7 |
EM |
4.2 |
2022-10-12 |
octamer |
1 |
H3.3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601_modified |
126 |
RNA polymerase II elongation complex transcribing a nucleosome (EC49B) |
Ehara, H., Kujirai, T., Shirouzu, M., Kurumizaka, H., Sekine, S.I. |
10.1126/science.abp9466 |
35981082 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
|
2022 |
DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, RNA polymerase II third largest subunit B44, part of central core, RNA polymerase II subunit B32, DNA-directed RNA polymerases I, II, and III subunit RPABC1, RNA polymerase subunit ABC23, common to RNA polymerases I, II, and III, RNA polymerase II subunit, DNA-directed RNA polymerases I, II, and III subunit RPABC3, RNA polymerase subunit ABC10-beta, common to RNA polymerases I, II, and III, RNA polymerase II subunit B12.5, RNA polymerase subunit ABC10-alpha, Transcription elongation factor 1 homolog, Transcription elongation factor SPT4, Transcription elongation factor SPT5, FACT complex subunit, FACT complex subunit POB3, Transcription elongation factor Spt6, Protein that interacts with Spt6p and copurifies with Spt5p and RNA polymerase II, Component of the Paf1p complex, RNAPII-associated chromatin remodeling Paf1 complex subunit, Leo1, RNAP II-associated protein, Constituent of Paf1 complex with RNA polymerase II, Paf1p, Hpr1p, Ctr9, Leo1, Rtf1 and Ccr4p |
Histone chaperones, RNA polymerases, FACT, DNA repair, Transcription factors, DNA replication, Transcription-associated, SPT4-SPT5 complex |
C4R4Y0, C4QZQ7, C4R7L2, C4R2U9, C4R3P8, C4R1V1, C4R9A1, C4R273, F2QPE6, C4R009, C4R3Z5, F2QMI1, C4QZ45, C4R0E6, C4R370, F2QPX0, F2QNN8, C4R7H2, C4R7L8, C4R6B2, F2QQ42, C4R3K1, C4R997, C4R1E6 |
P62805, P06899, P84243, P04908 |
0.207 |
| 2 |
7XTD |
EM |
3.9 |
2022-09-07 |
octamer |
1 |
H3.3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601_modified |
123 |
RNA polymerase II elongation complex transcribing a nucleosome (EC58oct) |
Ehara, H., Kujirai, T., Shirouzu, M., Kurumizaka, H., Sekine, S.I. |
10.1126/science.abp9466 |
35981082 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
|
2022 |
DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, RNA polymerase II third largest subunit B44, part of central core, RNA polymerase II subunit B32, DNA-directed RNA polymerases I, II, and III subunit RPABC1, RNA polymerase subunit ABC23, common to RNA polymerases I, II, and III, RNA polymerase II subunit, DNA-directed RNA polymerases I, II, and III subunit RPABC3, RNA polymerase subunit ABC10-beta, common to RNA polymerases I, II, and III, RNA polymerase II subunit B12.5, RNA polymerase subunit ABC10-alpha, Transcription elongation factor 1 homolog, Transcription elongation factor SPT4, Transcription elongation factor SPT5, FACT complex subunit, FACT complex subunit POB3, Transcription elongation factor Spt6, Protein that interacts with Spt6p and copurifies with Spt5p and RNA polymerase II, Component of the Paf1p complex, RNAPII-associated chromatin remodeling Paf1 complex subunit, Leo1, RNAP II-associated protein, Constituent of Paf1 complex with RNA polymerase II, Paf1p, Hpr1p, Ctr9, Leo1, Rtf1 and Ccr4p |
Histone chaperones, RNA polymerases, FACT, DNA repair, Transcription factors, DNA replication, Transcription-associated, SPT4-SPT5 complex |
C4R4Y0, C4QZQ7, C4R7L2, C4R2U9, C4R3P8, C4R1V1, C4R9A1, C4R273, F2QPE6, C4R009, C4R3Z5, F2QMI1, C4QZ45, C4R0E6, C4R370, C4QYQ8, F2QNN8, C4R7H2, C4R7L8, C4R6B2, F2QQ42, C4R3K1, C4R997, C4R1E6 |
P62805, P06899, P84243, P04908 |
0.221 |
| 3 |
7XTI |
EM |
3.9 |
2022-10-12 |
hexamer |
1 |
H3.3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601_modified |
85 |
RNA polymerase II elongation complex transcribing a nucleosome (EC58hex) |
Ehara, H., Kujirai, T., Shirouzu, M., Kurumizaka, H., Sekine, S.I. |
10.1126/science.abp9466 |
35981082 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
|
2022 |
DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, RNA polymerase II third largest subunit B44, part of central core, RNA polymerase II subunit B32, DNA-directed RNA polymerases I, II, and III subunit RPABC1, RNA polymerase subunit ABC23, common to RNA polymerases I, II, and III, RNA polymerase II subunit, DNA-directed RNA polymerases I, II, and III subunit RPABC3, RNA polymerase subunit ABC10-beta, common to RNA polymerases I, II, and III, RNA polymerase II subunit B12.5, RNA polymerase subunit ABC10-alpha, Transcription elongation factor 1 homolog, Transcription elongation factor SPT4, Transcription elongation factor SPT5, FACT complex subunit, FACT complex subunit POB3, Transcription elongation factor Spt6, Protein that interacts with Spt6p and copurifies with Spt5p and RNA polymerase II, Component of the Paf1p complex, RNAPII-associated chromatin remodeling Paf1 complex subunit, Leo1, RNAP II-associated protein, Constituent of Paf1 complex with RNA polymerase II, Paf1p, Hpr1p, Ctr9, Leo1, Rtf1 and Ccr4p |
Histone chaperones, RNA polymerases, FACT, DNA repair, Transcription factors, DNA replication, Transcription-associated, SPT4-SPT5 complex |
C4R4Y0, C4QZQ7, C4R7L2, C4R2U9, C4R3P8, C4R1V1, C4R9A1, C4R273, F2QPE6, C4R009, C4R3Z5, F2QMI1, C4QZ45, C4R0E6, C4R370, C4QYQ8, F2QNN8, C4R7H2, C4R7L8, C4R6B2, F2QQ42, C4R3K1, C4R997, C4R1E6 |
P62805, P06899, P84243, P04908 |
0.223 |
| 4 |
6HTS |
EM |
4.8 |
2018-11-07 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
150 |
Cryo-EM structure of the human INO80 complex bound to nucleosome |
Ayala, R., Willhoft, O., Aramayo, R.J., Wilkinson, M., McCormack, E.A., Ocloo, L., Wigley, D.B., Zhang, X. |
10.1038/s41586-018-0021-6 |
29643506 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
|
2018 |
RuvB-like 1, RuvB-like 2, Chromatin-remodeling ATPase INO80, Actin-related protein 5, INO80 complex subunit B |
INO80, DNA repair, DNA replication, Transcription-associated, Chromatin remodelers |
Q9Y265, Q9Y230, Q9ULG1, Q9H9F9, Q9C086 |
P62805, P06899, P04908, P68431 |
0.181 |
| 5 |
6UPK |
EM |
4.9 |
2019-12-11 |
hexamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601_modified |
72 |
Structure of FACT_subnucleosome complex 1 |
Liu, Y., Zhou, K., Zhang, N., Wei, H., Tan, Y.Z., Zhang, Z., Carragher, B., Potter, C.S., D'Arcy, S., Luger, K. |
10.1038/s41586-019-1820-0 |
31775157 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
|
2019 |
FACT complex subunit SPT16, FACT complex subunit SSRP1 |
Histone chaperones, FACT, DNA repair, DNA replication, Transcription-associated |
Q9Y5B9, Q08945 |
P62805, P62807, P68431, Q93077 |
0.203 |
| 6 |
6UPL |
EM |
7.4 |
2019-12-11 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601_modified |
79 |
Structure of FACT_subnucleosome complex 2 |
Liu, Y., Zhou, K., Zhang, N., Wei, H., Tan, Y.Z., Zhang, Z., Carragher, B., Potter, C.S., D'Arcy, S., Luger, K. |
10.1038/s41586-019-1820-0 |
31775157 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
|
2019 |
FACT complex subunit SPT16, FACT complex subunit SSRP1 |
Histone chaperones, FACT, DNA repair, DNA replication, Transcription-associated |
Q9Y5B9, Q08945 |
P62805, P62807, P68431, Q93077 |
0.173 |
| 7 |
7NKY |
EM |
3.2 |
2021-07-07 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601_modified |
148 |
RNA Polymerase II-Spt4/5-nucleosome-FACT structure |
Farnung, L., Ochmann, M., Engeholm, M., Cramer, P. |
10.1038/s41594-021-00578-6 |
33846633 |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
|
2021 |
DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB4, DNA-directed RNA polymerases I, II, and III subunit RPABC1, DNA-directed RNA polymerases I, II, and III subunit RPABC2, DNA-directed RNA polymerase II subunit RPB7, DNA-directed RNA polymerases I, II, and III subunit RPABC3, DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerases I, II, and III subunit RPABC5, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerases I, II, and III subunit RPABC4, FACT complex subunit POB3, FACT complex subunit SPT16, Chromatin elongation factor SPT4, Transcription elongation factor SPT5 |
Heterochromatin-associated, Histone chaperones, RNA polymerases, FACT, DNA repair, Transcription factors, DNA replication, Transcription-associated, Centromere-associated, SPT4-SPT5 complex |
P04050, P08518, P16370, P20433, P20434, P20435, P34087, P20436, P27999, P22139, P38902, P40422, Q04636, P32558, P32914, P27692 |
P02281, P84233, P06897, P62799 |
0.358 |
| 8 |
7Y60 |
EM |
3.8 |
2023-08-16 |
H3_H4_tetramer, H3_H4_tetramer |
2 |
canonical_H3 |
canonical_H4 |
|
|
|
601 |
108 |
Cryo-EM structure of human CAF1LC bound right-handed Di-tetrasome |
Liu, C.P., Yu, Z., Xiong, J., Hu, J., Song, A., Ding, D., Yu, C., Yang, N., Wang, M., Yu, J., Hou, P., Zeng, K., Li, Z., Zhang, Z., Zhang, X., Li, W., Zhang, Z., Zhu, B., Li, G., Xu, R.M. |
10.1126/science.add8673 |
37616371 |
Homo sapiens |
Homo sapiens |
|
|
|
2023 |
Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B |
Histone chaperones, DNA repair, DNA replication, CAF-1 |
Q13111, Q13112 |
P62805, P68431 |
0.304 |
| 9 |
7Y61 |
EM |
5.6 |
2023-08-16 |
H3_H4_tetramer, H3_H4_tetramer |
2 |
canonical_H3 |
canonical_H4 |
|
|
|
601 |
92 |
Cryo-EM structure of the two CAF1LCs bound right-handed Di-tetrasome |
Liu, C.P., Yu, Z., Xiong, J., Hu, J., Song, A., Ding, D., Yu, C., Yang, N., Wang, M., Yu, J., Hou, P., Zeng, K., Li, Z., Zhang, Z., Zhang, X., Li, W., Zhang, Z., Zhu, B., Li, G., Xu, R.M. |
10.1126/science.add8673 |
37616371 |
Homo sapiens |
Homo sapiens |
|
|
|
2023 |
Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B |
Histone chaperones, DNA repair, DNA replication, CAF-1 |
Q13111, Q13112 |
P62805, P68431 |
0.189 |
| 10 |
7ZI4 |
EM |
3.2 |
2023-04-19 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
158 |
Cryo-EM structure of the human INO80 complex bound to a WT nucleosome |
Vance, N.R., Ayala, R., Willhoft, O., Tvardovskiy, A., McCormack, E.A., Bartke, T., Zhang, X., Wigley, D.B. |
|
0 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
|
2023 |
RuvB-like 1, RuvB-like 2, Chromatin-remodeling ATPase INO80, Actin-related protein 5, INO80 complex subunit C, INO80 complex subunit B |
INO80, DNA repair, DNA replication, Transcription-associated, Chromatin remodelers |
Q9Y265, Q9Y230, Q9ULG1, Q9H9F9, Q6PI98, Q9C086 |
P62805, P06899, P04908, P68431 |
0.462 |
| 11 |
8J6S |
EM |
3.8 |
2023-08-16 |
H3_H4_tetramer, H3_H4_tetramer |
2 |
canonical_H3 |
canonical_H4 |
|
|
|
601 |
99 |
Cryo-EM structure of the single CAF-1 bound right-handed Di-tetrasome |
Liu, C.P., Yu, Z., Xiong, J., Hu, J., Song, A., Ding, D., Yu, C., Yang, N., Wang, M., Yu, J., Hou, P., Zeng, K., Li, Z., Zhang, Z., Zhang, X., Li, W., Zhang, Z., Zhu, B., Li, G., Xu, R.M. |
10.1126/science.add8673 |
37616371 |
Homo sapiens |
Homo sapiens |
|
|
|
2023 |
Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B |
Histone chaperones, DNA repair, DNA replication, CAF-1 |
Q13111, Q13112 |
P62805, P68431 |
0.301 |
| 12 |
8J6T |
EM |
6.6 |
2023-08-16 |
H3_H4_tetramer, H3_H4_tetramer |
2 |
canonical_H3 |
canonical_H4 |
|
|
|
601 |
92 |
Cryo-EM structure of the double CAF-1 bound right-handed Di-tetrasome |
Liu, C.P., Yu, Z., Xiong, J., Hu, J., Song, A., Ding, D., Yu, C., Yang, N., Wang, M., Yu, J., Hou, P., Zeng, K., Li, Z., Zhang, Z., Zhang, X., Li, W., Zhang, Z., Zhu, B., Li, G., Xu, R.M. |
10.1126/science.add8673 |
37616371 |
Homo sapiens |
Homo sapiens |
|
|
|
2023 |
Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B |
Histone chaperones, DNA repair, DNA replication, CAF-1 |
Q13111, Q13112 |
P62805, P68431 |
0.166 |
| 13 |
6OM3 |
X-ray |
3.3 |
2019-07-10 |
octamer, octamer |
2 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
146 |
Crystal structure of the Orc1 BAH domain in complex with a nucleosome core particle |
De Ioannes, P., Leon, V.A., Kuang, Z., Wang, M., Boeke, J.D., Hochwagen, A., Armache, K.J. |
10.1038/s41467-019-10609-y |
31263106 |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
|
2019 |
Origin recognition complex subunit 1 |
Transcription-associated, ORC, DNA replication |
P54784 |
P02281, P84233, P06897, P62799 |
- |
| 14 |
8SIY |
EM |
2.9 |
2023-08-02 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A |
canonical_H2B |
|
601 |
147 |
Origin Recognition Complex Associated (ORCA) protein bound to H4K20me3-nucleosome |
Sahu, S., Ekundayo, B.E., Kumar, A., Bleichert, F. |
10.15252/embj.2023114654 |
37551430 |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
Xenopus laevis |
|
2023 |
Leucine-rich repeat and WD repeat-containing protein 1, Origin recognition complex subunit 2 |
Heterochromatin-associated, ORC, DNA replication |
A0A140UHX1, Q75PQ8 |
P02281, P84233, P06897, P62799 |
0.497 |
| 15 |
7E9C |
EM |
3.5 |
2022-09-07 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
H2A.X |
canonical_H2B |
|
601 |
130 |
Cryo-EM structure of the 1:1 Orc1 BAH domain in complex with nucleosome |
Jiang, H., Yu, C., Liu, C.P., Han, X., Yu, Z., Xu, R.M. |
|
0 |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) |
|
2022 |
Origin recognition complex subunit 1 |
Transcription-associated, ORC, DNA replication |
P54784 |
P02309, P61830, P04912, P02294 |
0.311 |
| 16 |
7E9F |
EM |
4.0 |
2022-09-07 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
H2A.X |
canonical_H2B |
|
601 |
123 |
Cryo-EM structure of the 2:1 Orc1 BAH domain in complex with nucleosome |
Jiang, H., Yu, C., Liu, C.P., Han, X., Yu, Z., Xu, R.M. |
|
0 |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) |
|
2022 |
Origin recognition complex subunit 1 |
Transcription-associated, ORC, DNA replication |
P54784 |
P02309, P61830, P04912, P02294 |
0.319 |