0 |
9B3P |
EM |
3.00 |
2024-06-12 |
octamer |
1 |
H3.3 |
canonical_H4 |
H2A.Z |
canonical_H2B |
|
601 |
128 |
The cryo-EM structure of the H2A.Z-H3.3 double-variant nucleosome |
Jung, H., Sokolova, V., Lee, G., Stevens, V.R., Tan, D. |
10.3390/epigenomes8020021 |
38920622 |
Homo sapiens |
Xenopus laevis |
Mus musculus |
Xenopus laevis |
Xenopus laevis |
2024 |
|
|
|
P02281, P84243, P0C0S6, P62799 |
0.455 |
1 |
8X2X |
EM |
3.80 |
2025-03-19 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
H2A.Z |
canonical_H2B |
|
alphasat_146 |
146 |
The piccolo NuA4 bound to the H2A.Z nucleosome complex at pre-H4-acetylation state |
Wang, L., Zhang, H., Jia, Q., Li, W., Yang, C., Ma, L., Li, M., Lu, Y., Zhu, H., Zhu, P. |
10.1073/pnas.2414490122 |
40100634 |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Xenopus laevis |
2025 |
Histone acetyltransferase, Maltose/maltodextrin-binding periplasmic protein,Chromatin modification-related protein EAF6, glutathione transferase,Enhancer of polycomb-like protein, Chromatin modification-related protein |
Histone PTM writers, NuA4, Cell cycle, Transcription-associated, Histone_acetylation_writer |
Q08649, P0AEX9, Q540A3, P38806 |
Q12692, P02309, P02293, P61830 |
0.261 |
2 |
1F66 |
X-ray |
2.60 |
2000-11-27 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
H2A.Z |
canonical_H2B |
|
alphasat_146 |
146 |
2.6 A CRYSTAL STRUCTURE OF A NUCLEOSOME CORE PARTICLE CONTAINING THE VARIANT HISTONE H2A.Z |
Suto, R.K., Clarkson, M.J., Tremethick, D.J., Luger, K. |
10.1038/81971 |
11101893 |
Xenopus laevis |
Mus musculus |
Homo sapiens |
Xenopus laevis |
Xenopus laevis |
2000 |
|
|
|
P02281, P84233, P62806, P0C0S5 |
- |
3 |
7YRG |
EM |
4.20 |
2023-12-13 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
H2A.Z |
canonical_H2B |
|
alphasat_146 |
146 |
histone methyltransferase |
Huang, L., Wang, Y., Long, H., Zhu, H., Wen, Z., Zhang, L., Zhang, W., Guo, Z., Wang, L., Tang, F., Hu, J., Bao, K., Zhu, P., Li, G., Zhou, Z. |
10.1016/j.molcel.2023.07.001 |
37536340 |
Xenopus laevis |
Xenopus laevis |
Homo sapiens |
Xenopus laevis |
Xenopus laevis |
2023 |
[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B |
Histone_methylation_H4K20_writer, Histone PTM writers, Transcription-associated, Heterochromatin-associated, DNA repair |
Q4FZB7 |
P02281, P84233, P0C0S5, P62799 |
0.227 |
4 |
6JOU |
X-ray |
2.17 |
2020-03-25 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
H2A.Z |
canonical_H2B |
|
alphasat_146 |
146 |
Crystal structure of the human nucleosome containing H2A.Z.1 S42R |
Horikoshi, N., Kujirai, T., Sato, K., Kimura, H., Kurumizaka, H. |
10.1016/j.bbrc.2019.06.012 |
31186139 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2020 |
|
|
|
P68431, P06899, P0C0S5, P62805 |
- |
5 |
6M4D |
EM |
4.40 |
2020-09-23 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
H2A.Z |
canonical_H2B |
|
601 |
125 |
Structural mechanism of nucleosome dynamics governed by human histone variants H2A.B and H2A.Z.2.2 |
Zhou, M., Dai, L., Li, C., Shi, L., Huang, Y., Guo, Z., Wu, F., Zhu, P., Zhou, Z. |
10.15252/embj.2020105907 |
33073403 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2020 |
|
|
|
P68431, Q16778, Q71UI9, P62805 |
0.311 |
6 |
7YRD |
EM |
3.20 |
2023-08-16 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
H2A.Z |
canonical_H2B |
|
alphasat_146 |
146 |
histone methyltransferase |
Huang, L., Wang, Y., Long, H., Zhu, H., Wen, Z., Zhang, L., Zhang, W., Guo, Z., Wang, L., Tang, F., Hu, J., Bao, K., Zhu, P., Li, G., Zhou, Z. |
10.1016/j.molcel.2023.07.001 |
37536340 |
Xenopus laevis |
Xenopus laevis |
Homo sapiens |
Xenopus laevis |
Xenopus laevis |
2023 |
[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B |
Histone_methylation_H4K20_writer, Histone PTM writers, Transcription-associated, Heterochromatin-associated, DNA repair |
Q4FZB7 |
P06899, P0C0S5, Q71DI3, P62805 |
0.484 |
7 |
8X31 |
EM |
6.20 |
2025-03-19 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
H2A.Z |
canonical_H2B |
|
alphasat_146 |
146 |
The piccolo NuA4 bound to the H2A.Z nucleosome complex with Ac-CoA at resetting state |
Wang, L., Zhang, H., Jia, Q., Li, W., Yang, C., Ma, L., Li, M., Lu, Y., Zhu, H., Zhu, P. |
10.1073/pnas.2414490122 |
40100634 |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Xenopus laevis |
2025 |
Histone acetyltransferase, Maltose/maltodextrin-binding periplasmic protein,Chromatin modification-related protein EAF6, glutathione transferase,Enhancer of polycomb-like protein, Chromatin modification-related protein |
Histone PTM writers, NuA4, Cell cycle, Transcription-associated, Histone_acetylation_writer |
Q08649, P47128, Q540A3, P38806 |
Q12692, P02309, P02293, P61830 |
0.123 |
8 |
8X30 |
EM |
4.30 |
2025-03-19 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
H2A.Z |
canonical_H2B |
|
alphasat_146 |
146 |
Structure of piccolo NuA4 and H2A.Z nucleosome 2:1 complex |
Wang, L., Zhang, H., Jia, Q., Li, W., Yang, C., Ma, L., Li, M., Lu, Y., Zhu, H., Zhu, P. |
10.1073/pnas.2414490122 |
40100634 |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Xenopus laevis |
2025 |
Histone acetyltransferase, glutathione transferase,Enhancer of polycomb-like protein, Chromatin modification-related protein, Maltose/maltodextrin-binding periplasmic protein,Chromatin modification-related protein EAF6 |
Histone PTM writers, NuA4, Cell cycle, Transcription-associated, Histone_acetylation_writer |
Q08649, Q540A3, P38806, P47128 |
Q12692, P02309, P02293, P61830 |
0.165 |
9 |
7M1X |
EM |
3.70 |
2021-09-29 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
H2A.Z |
canonical_H2B |
|
601 |
136 |
Cryo-EM Structure of Nucleosome containing mouse histone variant H2A.Z |
Lewis, T.S., Sokolova, V., Jung, H., Ng, H., Tan, D. |
10.1093/nar/gkab907 |
34643712 |
Xenopus laevis |
Xenopus laevis |
Mus musculus |
Xenopus laevis |
Xenopus laevis |
2021 |
|
|
|
P02281, P0C0S6, P02302, P62799 |
0.391 |
10 |
8QZ0 |
EM |
3.80 |
2024-10-02 |
octamer |
1 |
H3.3 |
canonical_H4 |
H2A.X,H2A.Z |
canonical_H2B |
|
601 |
113 |
SWR1-hexasome-dimer complex |
Jalal, A.S.B., Girvan, P., Chua, E.Y.D., Liu, L., Wang, S., McCormack, E.A., Skehan, M.T., Knight, C.L., Rueda, D.S., Wigley, D.B. |
10.1016/j.molcel.2024.08.015 |
39226902 |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Xenopus laevis |
2024 |
Histone H2A.Z-specific chaperone CHZ1, Helicase SWR1, SWR1-complex protein 5, Actin-like protein ARP6, Vacuolar protein sorting-associated protein 71, RuvB-like protein 1, RuvB-like protein 2, Vacuolar protein sorting-associated protein 72 |
INO80, SRCAP (INO80), SWR1 (INO80), Chromatin remodelers, Histone chaperones, Euchromatin-associated, Transcription-associated |
P40019, Q05471, P38326, Q12509, Q03433, Q03940, Q12464, Q03388 |
P02293, Q12692, P02309, P04911, P61830 |
0.293 |
11 |
5B31 |
X-ray |
2.20 |
2016-08-03 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
canonical_H2A,H2A.Z |
canonical_H2B |
|
alphasat_146 |
146 |
The crystal structure of the heterotypic H2AZ/H2A nucleosome with H3.1. |
Horikoshi, N., Arimura, Y., Taguchi, H., Kurumizaka, H. |
10.1098/rsob.160127 |
27358293 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2016 |
|
|
|
P68431, P06899, P0C0S5, P04908, P62805 |
- |
12 |
5B33 |
X-ray |
2.92 |
2016-08-03 |
octamer |
1 |
H3.3 |
canonical_H4 |
H2A.Z |
canonical_H2B |
|
alphasat_146 |
146 |
The crystal structure of the H2AZ nucleosome with H3.3. |
Horikoshi, N., Arimura, Y., Taguchi, H., Kurumizaka, H. |
10.1098/rsob.160127 |
27358293 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2016 |
|
|
|
P84243, P0C0S5, P06899, P62805 |
- |
13 |
8UXQ |
EM |
6.30 |
2024-09-25 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
H2A.Z |
canonical_H2B |
|
601 |
97 |
Structure of Heterochromatin Protein 1 (HP1) alpha in complex with an H2A.Z nucleosome |
Sokolova, V., Miratsky, J., Svetlov, V., Brenowitz, M., Vant, J., Lewis, T.S., Dryden, K., Lee, G., Sarkar, S., Nudler, E., Singharoy, A., Tan, D. |
10.1016/j.str.2024.09.013 |
39383876 |
Xenopus laevis |
Xenopus laevis |
Mus musculus |
Xenopus laevis |
Xenopus laevis |
2024 |
Chromobox protein homolog 5 |
Histone_methylation_H3K9_reader, Histone PTM readers, Heterochromatin-associated, Transcription-associated |
P45973 |
P02281, P84233, P0C0S6, P62799 |
0.143 |
14 |
8THU |
EM |
3.10 |
2023-09-06 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
H2A.Z |
canonical_H2B |
|
601 |
145 |
Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1 |
Abini-Agbomson, S., Gretarsson, K., Shih, R.M., Hsieh, L., Lou, T., De Ioannes, P., Vasilyev, N., Lee, R., Wang, M., Simon, M.D., Armache, J.P., Nudler, E., Narlikar, G., Liu, S., Lu, C., Armache, K.J. |
10.1016/j.molcel.2023.07.020 |
37595555 |
Xenopus laevis |
Xenopus laevis |
Homo sapiens |
Xenopus laevis |
Xenopus laevis |
2023 |
|
|
|
P02281, P84233, P0C0S5, P62799 |
0.508 |
15 |
3WA9 |
X-ray |
3.07 |
2013-12-18 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
H2A.Z |
canonical_H2B |
|
alphasat_146 |
146 |
The nucleosome containing human H2A.Z.1 |
Horikoshi, N., Sato, K., Shimada, K., Arimura, Y., Osakabe, A., Tachiwana, H., Hayashi-Takanaka, Y., Iwasaki, W., Kagawa, W., Harata, M., Kimura, H., Kurumizaka, H. |
10.1107/S090744491302252X |
24311584 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2013 |
|
|
|
P68431, P06899, P0C0S5, P62805 |
- |
16 |
8X2Y |
EM |
4.10 |
2025-03-19 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
H2A.Z |
canonical_H2B |
|
alphasat_146 |
146 |
The class1 of piccolo NuA4 bound to the H2A.Z nucleosome complex at harboring state |
Wang, L., Zhang, H., Jia, Q., Li, W., Yang, C., Ma, L., Li, M., Lu, Y., Zhu, H., Zhu, P. |
10.1073/pnas.2414490122 |
40100634 |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Xenopus laevis |
2025 |
Histone acetyltransferase, Maltose/maltodextrin-binding periplasmic protein,Chromatin modification-related protein EAF6, glutathione transferase,Enhancer of polycomb-like protein, Chromatin modification-related protein |
Histone PTM writers, NuA4, Cell cycle, Transcription-associated, Histone_acetylation_writer |
Q08649, P0AEX9, P08515, P38806 |
Q12692, P02309, P02293, P61830 |
0.229 |
17 |
3WAA |
X-ray |
3.20 |
2013-12-18 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
H2A.Z |
canonical_H2B |
|
alphasat_146 |
146 |
The nucleosome containing human H2A.Z.2 |
Horikoshi, N., Sato, K., Shimada, K., Arimura, Y., Osakabe, A., Tachiwana, H., Hayashi-Takanaka, Y., Iwasaki, W., Kagawa, W., Harata, M., Kimura, H., Kurumizaka, H. |
10.1107/S090744491302252X |
24311584 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2013 |
|
|
|
P68431, P06899, Q71UI9, P62805 |
- |
18 |
8JHF |
EM |
3.68 |
2023-11-15 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
H2A.Z |
canonical_H2B |
|
601 |
160 |
Native SUV420H1 bound to 167-bp nucleosome |
Lin, F., Zhang, R., Shao, W., Lei, C., Ma, M., Zhang, Y., Wen, Z., Li, W. |
10.1038/s41421-023-00620-5 |
38052811 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2023 |
Histone-lysine N-methyltransferase KMT5B |
Histone_methylation_H4K20_writer, Histone PTM writers, Transcription-associated, Heterochromatin-associated, DNA repair |
Q4FZB7 |
O60814, P68431, P0C0S5, P62805 |
0.433 |
19 |
5Z30 |
X-ray |
2.45 |
2018-07-18 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
H2A.Z |
canonical_H2B |
|
alphasat_146 |
146 |
The crystal structure of the nucleosome containing a cancer-associated histone H2A.Z R80C mutant |
Arimura, Y., Ikura, M., Fujita, R., Noda, M., Kobayashi, W., Horikoshi, N., Sun, J., Shi, L., Kusakabe, M., Harata, M., Ohkawa, Y., Tashiro, S., Kimura, H., Ikura, T., Kurumizaka, H. |
10.1093/nar/gky661 |
30053102 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2018 |
|
|
|
P68431, P06899, P0C0S5, P62805 |
- |
20 |
5B32 |
X-ray |
2.35 |
2016-08-03 |
octamer |
1 |
H3.3 |
canonical_H4 |
canonical_H2A,H2A.Z |
canonical_H2B |
|
alphasat_146 |
146 |
The crystal structure of the heterotypic H2AZ/H2A nucleosome with H3.3. |
Horikoshi, N., Arimura, Y., Taguchi, H., Kurumizaka, H. |
10.1098/rsob.160127 |
27358293 |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Homo sapiens |
Xenopus laevis |
2016 |
|
|
|
P84243, P06899, P0C0S5, P04908, P62805 |
- |
21 |
8X2Z |
EM |
3.90 |
2025-03-19 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
H2A.Z |
canonical_H2B |
|
alphasat_146 |
146 |
The class2 of piccolo NuA4 bound to the H2A.Z nucleosome complex at harboring state |
Wang, L., Zhang, H., Jia, Q., Li, W., Yang, C., Ma, L., Li, M., Lu, Y., Zhu, H., Zhu, P. |
10.1073/pnas.2414490122 |
40100634 |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Xenopus laevis |
2025 |
Histone acetyltransferase, Maltose/maltodextrin-binding periplasmic protein,Chromatin modification-related protein EAF6, glutathione transferase,Enhancer of polycomb-like protein, Chromatin modification-related protein |
Histone PTM writers, NuA4, Cell cycle, Transcription-associated, Histone_acetylation_writer |
Q08649, P47128, Q540A3, P38806 |
Q12692, P02309, P02293, P61830 |
0.237 |
22 |
8X32 |
EM |
4.40 |
2025-03-19 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
H2A.Z |
canonical_H2B |
|
alphasat_146 |
146 |
The piccolo NuA4 bound to the H2A.Z nucleosome-H4KQ Complex with Ac-CoA at resetting state |
Wang, L., Zhang, H., Jia, Q., Li, W., Yang, C., Ma, L., Li, M., Lu, Y., Zhu, H., Zhu, P. |
10.1073/pnas.2414490122 |
40100634 |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Saccharomyces cerevisiae |
Xenopus laevis |
2025 |
Histone acetyltransferase, Maltose/maltodextrin-binding periplasmic protein,Chromatin modification-related protein EAF6, glutathione transferase,Enhancer of polycomb-like protein, Chromatin modification-related protein |
Histone PTM writers, NuA4, Cell cycle, Transcription-associated, Histone_acetylation_writer |
Q08649, P47128, Q540A3, P38806 |
Q12692, P02309, P02293, P61830 |
0.114 |
23 |
8T9F |
EM |
2.60 |
2023-09-06 |
octamer |
1 |
canonical_H3 |
canonical_H4 |
H2A.Z |
canonical_H2B |
|
601 |
122 |
Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1 |
Abini-Agbomson, S., Gretarsson, K., Shih, R.M., Hsieh, L., Lou, T., De Ioannes, P., Vasilyev, N., Lee, R., Wang, M., Simon, M.D., Armache, J.P., Nudler, E., Narlikar, G., Liu, S., Lu, C., Armache, K.J. |
10.1016/j.molcel.2023.07.020 |
37595555 |
Xenopus laevis |
Xenopus laevis |
Homo sapiens |
Xenopus laevis |
Xenopus laevis |
2023 |
Histone-lysine N-methyltransferase KMT5B |
Histone_methylation_H4K20_writer, Histone PTM writers, Transcription-associated, Heterochromatin-associated, DNA repair |
Q4FZB7 |
P02281, P84233, P0C0S5, P62799 |
0.516 |